Genetics: From Genes to Genomes 6th Edition
Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. This edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed.
Genetics: From Genes to Genomes represents a new approach to an undergraduate course in genetics. It reflects the way we, the authors, currently view the molecular basis of life. We integrate:
∙ Formal genetics: the rules by which genes are transmitted.
∙ Molecular genetics: the structure of DNA and how it directs the structure of proteins.
∙ Digital analysis and genomics: recent technologies that allow a comprehensive analysis of the entire gene set and its expression in an organism.
∙ Human genetics: how genes contribute to health and diseases, including cancer.
∙ The unity of life-forms: the synthesis of information from many different organisms into coherent models.
∙ Molecular evolution: the molecular mechanisms by which biological systems, whole organisms, and populations have evolved and diverged.
About the Author
Dr. Janice Fischer is a Professor at The University of Texas at Austin, where she is an award-winning teacher of genetics and Director of the Biology Instructional Office. She received her Ph.D. in Biochemistry and Molecular Biology from Harvard University, and did postdoctoral research at The University of California at Berkeley and The Whitehead Institute at MIT. In her research, Dr. Fischer uses fruit flies to examine the roles of ubiquitin and endocytosis in cell signaling during development.
Table of Contents
Chapter 1 Genetics: The Study of Biological Information
Chapter 2 Mendel’s Principles of Heredity
Chapter 3 Extensions to Mendel’s Laws
Chapter 4 The Chromosome Theory of Inheritance
Chapter 5 Linkager Recombination, and the Mapping of Genes on Chromosomes
Chapter 6 DNA Structurer Replication, and Recombination
Chapter 7 Anatomy and Function of a Gene: Dissection Through Mutation
Chapter 8 Gene Expression: The Flow of Information from DNA to RNA to Protein
Chapter 9 Digital Analysis of DNA
Chapter 10 Genome Annotation
Chapter 11 Analyzing Genomic Variation
Chapter 12 The Eukaryotic Chromosome
Chapter 13 Chromosomal Rearrangements and Changes in Chromosome Number
Chapter 14 Bacterial Genetics
Chapter 15 Organellar Inheritance
Chapter 16 Gene Regulation in Prokaryotes
Chapter 17 Gene Regulation in Eukaryotes
Chapter 18 Manipulating the Genomes of Eukaryotes
Chapter 19 The Genetic Analysis of Development
Chapter 20 The Genetics of Cancer
Chapter 21 Variation and Selection in Populations
Chapter 22 The Genetics of Complex Traits