Diagnostic Pathology: Soft Tissue Tumors 3rd Edition

Cover image
Title page
Table of Contents
Copyright
Dedication
Contributing Authors
Preface
Acknowledgments
Sections
SECTION 1: SOFT TISSUE INTRODUCTION
INTRODUCTION AND OVERVIEW
Chapter 1: Gross Examination
Introduction
Clinical Findings
Grossing Procedure
Chapter 2: Grading and Staging
Grading and Staging Systems
Histologic Features Evaluated in Grading (FNCLCC)
ANCILLARY TECHNIQUES
Chapter 3: Soft Tissue Immunohistochemistry
Chapter 4: Molecular Features of Soft Tissue Tumors
SECTION 2: DIAGNOSTIC APPROACH TO SOFT TISSUE TUMORS
OVERVIEW
Chapter 5: Biopsy and Resection of Soft Tissue Tumors
Overview
Biopsy Specimens
Resection Specimens
Special Topics
CLINICAL APPROACH
Chapter 6: Age- and Location-Based Approach to Diagnosis
Directions
Age-Based Approach
Location-Based Approach
Gastrointestinal Mesenchymal Tumors (Most Common by Location)
Mesenchymal Tumors Involving Lymph Nodes (Most Common)
HISTOLOGIC APPROACH
Chapter 7: Pattern-Based Approach to Diagnosis
Directions
Monomorphic Spindle Cell Patterns
Pleomorphic Spindle Cell Patterns
Epithelioid Cell Patterns
Other Patterns
Chapter 8: Feature-Based Approach to Diagnosis
DIRECTIONS
Cytologic Features
Inflammatory Component
Multinucleated Cells
Nuclear Features
Stromal Findings
Structures
Vasculature
SECTION 3: TUMORS OF ADIPOSE TISSUE
BENIGN
Chapter 9: Lipoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 10: Lipomatosis of Nerve
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
Chapter 11: Synovial Lipomatosis
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
Chapter 12: Angiolipoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 13: Spindle Cell/Pleomorphic Lipoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 14: Chondroid Lipoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 15: Myolipoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 16: Hibernoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 17: Myelolipoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 18: Lipoblastoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 19: Atypical Spindle Cell Lipomatous Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
INTERMEDIATE, LOCALLY AGGRESSIVE
Chapter 20: Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
MALIGNANT
Chapter 21: Dedifferentiated Liposarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 22: Myxoid Liposarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 23: Pleomorphic Liposarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
SECTION 4: FIBROBLASTIC/MYOFIBROBLASTIC LESIONS
BENIGN
Chapter 24: Nodular Fasciitis
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 25: Proliferative Fasciitis/Myositis
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 26: Ischemic Fasciitis
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 27: Myositis Ossificans
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 28: Fibroosseous Pseudotumor of Digit
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
Chapter 29: Fibroma of Tendon Sheath
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 30: Desmoplastic Fibroblastoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 31: Elastofibroma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 32: Angiofibroma of Soft Tissue
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 33: Mammary-Type Myofibroblastoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 34: Intranodal Palisaded Myofibroblastoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 35: Pleomorphic Fibroma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 36: Dermatomyofibroma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 37: Storiform Collagenoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 38: Keloid
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 39: Nuchal-Type Fibroma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
INTERMEDIATE (LOCALLY AGGRESSIVE)
Chapter 40: Palmar/Plantar Fibromatosis
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 41: Desmoid-Type Fibromatosis
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
INTERMEDIATE (RARELY METASTASIZING)
Chapter 42: Dermatofibrosarcoma Protuberans
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 43: Solitary Fibrous Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 44: Low-Grade Myofibroblastic Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 45: Inflammatory Myofibroblastic Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 46: Myxoinflammatory Fibroblastic Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 47: Superficial CD34(+) Fibroblastic Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
MALIGNANT
Chapter 48: Adult-Type Fibrosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 49: Myxofibrosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 50: Low-Grade Fibromyxoid Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 51: Sclerosing Epithelioid Fibrosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 5: PEDIATRIC FIBROBLASTIC/MYOFIBROBLASTIC TUMORS
BENIGN
Chapter 52: Fibrous Hamartoma of Infancy
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 53: Calcifying Aponeurotic Fibroma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
Chapter 54: Calcifying Fibrous Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 55: Inclusion Body Fibromatosis
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 56: Hyaline Fibromatosis Syndrome
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
Chapter 57: Fibromatosis Colli
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 58: Gardner Fibroma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
INTERMEDIATE (LOCALLY AGGRESSIVE)
Chapter 59: Lipofibromatosis
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 60: Giant Cell Fibroblastoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
INTERMEDIATE (RARELY METASTASIZING)
Chapter 61: Infantile Fibrosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 6: FIBROHISTIOCYTIC, HISTIOCYTIC, AND DENDRITIC CELL TUMORS
BENIGN
Chapter 62: Dermatofibroma and Fibrous Histiocytoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 63: Deep Benign Fibrous Histiocytoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 64: Localized-Type Tenosynovial Giant Cell Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 65: Diffuse-Type Tenosynovial Giant Cell Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 66: Cellular Neurothekeoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 67: Xanthomas
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 68: Solitary (Juvenile) Xanthogranuloma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 69: Reticulohistiocytoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 70: Deep Granuloma Annulare
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 71: Rheumatoid Nodule
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 72: Langerhans Cell Histiocytosis
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 73: Extranodal Rosai-Dorfman Disease
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 74: Crystal-Storing Histiocytosis
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
INTERMEDIATE (RARELY METASTASIZING)
Chapter 75: Plexiform Fibrohistiocytic Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 76: Giant Cell Tumor of Soft Tissue
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
MALIGNANT
Chapter 77: Histiocytic Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 78: Follicular Dendritic Cell Sarcoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 79: Interdigitating Dendritic Cell Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 7: SMOOTH MUSCLE TUMORS
BENIGN
Chapter 80: Smooth Muscle Hamartoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 81: Superficial Leiomyoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 82: Deep Leiomyoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
INTERMEDIATE
Chapter 83: Epstein-Barr Virus-Associated Smooth Muscle Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
MALIGNANT
Chapter 84: Leiomyosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 8: PERICYTIC (PERIVASCULAR) TUMORS
BENIGN
Chapter 85: Glomus Tumors (and Variants)
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 86: Myopericytoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 87: Myofibroma and Myofibromatosis
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 88: Angioleiomyoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 9: TUMORS OF SKELETAL MUSCLE
BENIGN
Chapter 89: Focal Myositis
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 90: Adult Rhabdomyoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 91: Fetal Rhabdomyoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 92: Genital Rhabdomyoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 93: Cardiac Rhabdomyoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
MALIGNANT
Chapter 94: Embryonal Rhabdomyosarcoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 95: Alveolar Rhabdomyosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 96: Spindle Cell Rhabdomyosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 97: Sclerosing Rhabdomyosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 98: Pleomorphic Rhabdomyosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 99: Epithelioid Rhabdomyosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 10: VASCULAR TUMORS (INCLUDING LYMPHATICS)
BENIGN
Chapter 100: Papillary Endothelial Hyperplasia
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 101: Bacillary Angiomatosis
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 102: Congenital Hemangioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 103: Infantile Hemangioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 104: Lobular Capillary Hemangioma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 105: Epithelioid Hemangioma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 106: Spindle Cell Hemangioma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 107: Intramuscular Hemangioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 108: Hobnail Hemangioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 109: Acquired Tufted Angioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 110: Microvenular Hemangioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 111: Sinusoidal Hemangioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 112: Glomeruloid Hemangioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 113: Angiomatosis
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 114: Lymphangioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 115: Massive Localized Lymphedema
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
Chapter 116: Atypical Vascular Lesion
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
INTERMEDIATE (LOCALLY AGGRESSIVE)
Chapter 117: Kaposiform Hemangioendothelioma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
INTERMEDIATE (RARELY METASTASIZING)
Chapter 118: Papillary Intralymphatic Angioendothelioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 119: Retiform Hemangioendothelioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 120: Composite Hemangioendothelioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
Chapter 121: Pseudomyogenic Hemangioendothelioma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
MALIGNANT
Chapter 122: Epithelioid Hemangioendothelioma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 123: Angiosarcoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 124: Kaposi Sarcoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
SECTION 11: CHONDROOSSEOUS TUMORS
BENIGN
Chapter 125: Soft Tissue Chondroma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 126: Synovial Chondromatosis
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
MALIGNANT
Chapter 127: Extraskeletal Osteosarcoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 128: Extraskeletal Mesenchymal Chondrosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 12: PERIPHERAL NERVE SHEATH TUMORS
BENIGN
Chapter 129: Solitary Circumscribed Neuroma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 130: Schwannoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 131: Neurofibroma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 132: Perineurioma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 133: Hybrid Nerve Sheath Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 134: Granular Cell Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 135: Dermal Nerve Sheath Myxoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 136: Ganglioneuroma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 137: Neuromuscular Choristoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
INTERMEDIATE
Chapter 138: Melanotic Schwannoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
MALIGNANT
Chapter 139: Malignant Peripheral Nerve Sheath Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 140: Epithelioid Malignant Peripheral Nerve Sheath Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 141: Ectomesenchymoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 13: GENITAL STROMAL TUMORS
Chapter 142: Fibroepithelial Stromal Polyp
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 143: Angiomyofibroblastoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 144: Cellular Angiofibroma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 145: Deep (Aggressive) Angiomyxoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 14: TUMORS OF MESOTHELIAL CELLS
BENIGN
Chapter 146: Adenomatoid Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 147: Multicystic Peritoneal Mesothelioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 148: Well-Differentiated Papillary Mesothelioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
MALIGNANT
Chapter 149: Malignant Mesothelioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 15: HEMATOPOIETIC TUMORS IN SOFT TISSUE
Chapter 150: Solitary Extramedullary Plasmacytoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 151: Myeloid Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 152: Lymphoma of Soft Tissue
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 16: TUMORS OF UNCERTAIN DIFFERENTIATION
BENIGN
Chapter 153: Intramuscular Myxoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 154: Juxtaarticular Myxoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 155: Superficial Angiomyxoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 156: Acral Fibromyxoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 157: Pleomorphic Hyalinizing Angiectatic Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 158: Aneurysmal Bone Cyst of Soft Tissue
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 159: Ectopic Hamartomatous Thymoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
INTERMEDIATE (LOCALLY AGGRESSIVE)
Chapter 160: Hemosiderotic Fibrolipomatous Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
INTERMEDIATE (RARELY METASTASIZING)
Chapter 161: Atypical Fibroxanthoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 162: Angiomatoid Fibrous Histiocytoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 163: Ossifying Fibromyxoid Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 164: Myoepithelioma of Soft Tissue
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 165: Phosphaturic Mesenchymal Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
MALIGNANT
Chapter 166: Synovial Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 167: Epithelioid Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 168: Alveolar Soft Part Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 169: Clear Cell Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 170: Perivascular Epithelioid Cell Tumor (PEComa)
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 171: Desmoplastic Small Round Cell Tumor
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 172: Extraskeletal Ewing Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 173: Extraskeletal Myxoid Chondrosarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 174: Extrarenal Rhabdoid Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 175: Intimal Sarcoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 17: UNDIFFERENTIATED/UNCLASSIFIED SARCOMAS
Chapter 176: Undifferentiated Pleomorphic Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 177: Undifferentiated Round Cell Sarcoma With CIC-DUX4 Translocation
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 178: BCOR-CCNB3 Fusion-Positive Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
SECTION 18: MESENCHYMAL TUMORS OF GASTROINTESTINAL TRACT
Chapter 179: Benign Neural Gastrointestinal Polyps
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 180: Gastrointestinal Stromal Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 181: Gastrointestinal Schwannoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 182: Gastrointestinal Smooth Muscle Neoplasms
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 183: Inflammatory Fibroid Polyp
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 184: Gangliocytic Paraganglioma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 185: Plexiform Fibromyxoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 186: Malignant Gastrointestinal Neuroectodermal Tumor
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
SECTION 19: OTHER ENTITIES
BENIGN
Chapter 187: Amyloidoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 188: Ganglion Cyst
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 189: Tumoral Calcinosis
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
DIFFERENTIAL DIAGNOSIS
Chapter 190: Idiopathic Tumefactive Fibroinflammatory Lesions
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 191: Cardiac Myxoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 192: Cardiac Fibroma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 193: Congenital Granular Cell Epulis
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 194: Nasopharyngeal Angiofibroma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 195: Sinonasal Glomangiopericytoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 196: Ectopic Meningioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 197: Glial Heterotopia
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
INTERMEDIATE
Chapter 198: Paraganglioma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 199: Peripheral Hemangioblastoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 200: Melanotic Neuroectodermal Tumor of Infancy
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 201: Ependymoma of Soft Tissue
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
MALIGNANT
Chapter 202: Metastatic Tumors to Soft Tissue Sites
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 203: Neuroblastoma and Ganglioneuroblastoma
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 204: Extraaxial Soft Tissue Chordoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
IMAGING
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 205: Undifferentiated Embryonal Sarcoma of Liver
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 206: Primary Pulmonary Myxoid Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC CHECKLIST
Chapter 207: Biphenotypic Sinonasal Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 208: Spindle Epithelial Tumor With Thymus-Like Differentiation
KEY FACTS
TERMINOLOGY
ETIOLOGY/PATHOGENESIS
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
Chapter 209: Low-Grade Endometrial Stromal Sarcoma
KEY FACTS
TERMINOLOGY
CLINICAL ISSUES
MACROSCOPIC
MICROSCOPIC
ANCILLARY TESTS
DIFFERENTIAL DIAGNOSIS
INDEX

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