Essential Cell Biology Fifth Edition

Essential Cell Biology 5th Edition:

This text features lively, clear writing and exceptional illustrations, making it the ideal textbook for a first course in both cell and molecular biology. Thoroughly revised and updated, the Fifth Edition maintains its focus on the latest cell biology research. For the first time ever, Essential Cell Biology will come with access to Smartwork5, Norton’s innovative online homework platform, creating a more complete learning experience.

Additional ISBNs:

0393428648, 0393680363, 978-0393428643 , 978-0393680362, 9780393428643, 9780393680362

Contents

Front Matter
Half Title
Title Page
Copyright
Preface
Acknowledgments
About the Authors
Contents
Chapter 1 – Cells: The Fundamental Units of Life
Unity and Diversity of Cells
Cells Under the Microscope
The Prokaryotic Cell
The Eukaryotic Cell
Model Organisms
Chapter 2 – Chemical Components of Cells
Chemical Bonds
Small Molecules in Cells
Macromolecules in Cells
Chapter 3 – Energy, Catalysis, and Biosynthesis
The Use of Energy by Cells
Free Energy and Catalysis
Activated Carriers and Biosynthesis
Chapter 4 – Protein Structure and Function
The Shape and Structure of Proteins
How Proteins Work
How Proteins are Controlled
How Proteins are Studied
Chapter 5 – DNA and Chromosomes
The Structure of DNA
The Structure of Eukaryotic Chromosomes
The Regulation of Chromosome Structure
Chapter 6 – DNA Replication and Repair
DNA Replication
DNA Repair
Chapter 7 – From DNA to Protein: How Cells Read the Genome
From DNA to RNA
From RNA to Protein
RNA and the Origins of Life
Chapter 8 – Control of Gene Expression
An Overview of Gene Expression
How Transcription Is Regulated
Generating Specialized Cell Types
Post-Transcriptional Controls
Chapter 9 – How Genes and Genomes Evolve
Generating Genetic Variation
Reconstructing Life’s Family Tree
Mobile Genetic Elements and Viruses
Examining the Human Genome
Chapter 10 – Analyzing the Structure and Function of Genes
Isolating and Cloning DNA Molecules
DNA Cloning by PCR
Sequencing DNA
Exploring Gene Function
Chapter 11 – Membrane Structure
The Lipid Bilayer
Membrane Proteins
Chapter 12 – Transport Across Cell Membranes
Principles of Transmembrane Transport
Transporters and Their Functions
Ion Channels and the Membrane Potential
Ion Channels and Nerve Cell Signaling
Chapter 13 – How Cells Obtain Energy from Food
The Breakdown and Utilization of Sugars and Fats
Regulation of Metabolism
Chapter 14 – Energy Generation in Mitochondria and Chloroplasts
Mitochondria and Oxidative Phosphorylation
Molecular Mechanisms of Electron Transport and Proton Pumping
Chloroplasts and Photosynthesis
The Evolution of Energy-Generating Systems
Chapter 15 – Intracellular Compartments and Protein Transport
Membrane-Enclosed Organelles
Protein Sorting
Vesicular Transport
Secretory Pathways
Endocytic Pathways
Chapter 16 – Cell Signaling
General Principles of Cell Signaling
G-Protein-Coupled Receptors
Enzyme-Coupled Receptors
Chapter 17 – Cytoskeleton
Intermediate Filaments
Microtubules
Actin Filaments
Muscle Contraction
Chapter 18 – The Cell-Division Cycle
Overview of the Cell Cycle
The Cell-Cycle Control System
G1 Phase
S Phase
M Phase
Mitosis
Cytokinesis
Control of Cell Numbers and Cell Size
Chapter 19 – Sexual Reproduction and Genetics
The Benefits of Sex
Meiosis and Fertilization
Mendel and the Laws of Inheritance
Genetics as an Experimental Tool
Exploring Human Genetics
Chapter 20 – Cell Communities: Tissues, Stem Cells, and Cancer
Extracellular Matrix and Connective Tissues
Epithelial Sheets and Cell Junctions
Stem Cells and Tissue Renewal
Cancer
Answers
Glossary
Index

About the Author

Bruce Alberts, Karen Hopkin, Alexander Johnson, David Morgan, Martin Raff , Keith Roberts, Peter Walter

Bruce Alberts received his PhD from Harvard University and is the Chancellor’s Leadership Chair in Biochemistry and Biophysics for Science and Education, University of California, San Francisco. He was the editor in chief of Science magazine from 2008 until 2013, and for 12 years he served as president of the U.S. National Academy of Sciences (1993–2005).
Karen Hopkin received her PhD in biochemistry from the Albert Einstein College of Medicine and is a science writer in Somerville, Massachusetts. She is a regular columnist for The Scientist and a contributor to Scientific American‘s daily podcast, “60-Second Science.”
Alexander Johnson received his PhD from Harvard University and is a professor of microbiology and immunology at the University of California, San Francisco. He is a member of the National Academy of Sciences.
David Morgan received his PhD from the University of California, San Francisco, and is a professor in the Department of Physiology as well as the vice dean for research for the School of Medicine. Dave is a fellow of the Royal Society of London.
Martin Raff received his MD from McGill University and is emeritus professor of biology at the Medical Research Council Laboratory for Molecular Cell Biology at University College London. He is a foreign member of the National Academy of Sciences.