Case Studies in Immunology: A Clinical Companion 7th Edition

Case Studies in Immunology: A Clinical Companion Seventh Edition:

The perfect clinical companion for your immunology course

Case Studies in Immunology presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. Each case history is preceded by essential scientific facts about the immunological mechanisms of that specific disorder. The cases themselves demonstrate how immunological problems are deconstructed in the clinic and each one is followed by a concise summary of the clinical finding with questions that serve as discussion points.

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∗ eText ISBN: 1324033304, 978-1324033301, 9781324033301

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Contents

Preface
Contents
Case 1: X-linked Agammaglobulinemia
Case 2: CD40 Ligand Deficiency
Case 3: Activation-Induced Cytidine Deaminase Deficiency
Case 4: Common Variable Immunodeficiency
Case 5: X-linked Severe Combined Immunodeficiency
Case 6: Adenosine Deaminase Deficiency
Case 7: Omenn Syndrome
Case 8: MHC Class II Deficiency
Case 9: DiGeorge Syndrome
Case 10: Acquired Immune Deficiency Syndrome (AIDS)
Case 11: Graft-Versus-Host Disease
Case 12: MHC Class I Deficiency
Case 13: X-linked Lymphoproliferative Syndrome
Case 14: Hemophagocytic Lymphohistiocytosis
Case 15: Chediak–Higashi Syndrome
Case 16: Wiskott–Aldrich Syndrome
Case 17: Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy (APECED)
Case 18: Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease
Case 19: Autoimmune Lymphoproliferative Syndrome (ALPS)
Case 20: Hyper IgE Syndrome
Case 21: Ataxia-Telangiectasia
Case 22: Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome (WHIM Syndrome)
Case 23: X-linked Hypohidrotic Ectodermal Dysplasia and Immunodeficiency
Case 24: Interferon-? Receptor Deficiency
Case 25: Severe Congenital Neutropenia
Case 26: Chronic Granulomatous Disease
Case 27: Leukocyte Adhesion Deficiency
Case 28: Recurrent Herpes Simplex Encephalitis
Case 29: Interleukin 1 Receptor-Associated Kinase 4 Deficiency
Case 30: Congenital Asplenia
Case 31: Hereditary Angioedema
Case 32: Deficiency of the C8 Complement Component
Case 33: Hereditary Periodic Fever Syndromes
Case 34: Systemic Juvenile Idiopathic Arthritis
Case 35: Rheumatoid Arthritis
Case 36: Systemic Lupus Erythematosus
Case 37: Crohn’s Disease
Case 38: Multiple Sclerosis
Case 39: Autoimmune Hemolytic Anemia
Case 40: Myasthenia Gravis
Case 41: Pemphigus Vulgaris
Case 42: Celiac Disease
Case 43: Acute Infectious Mononucleosis
Case 44: Hemolytic Disease of the Newborn
Case 45: Toxic Shock Syndrome
Case 46: Lepromatous Leprosy
Case 47: Allergic Asthma
Case 48: Drug-induced Serum Sickness
Case 49: Contact Sensitivity to Poison Ivy
Case 50: Dedicator of Cytokinesis 8 Deficiency
Case 51: Activated PI3KD Syndrome (APDS)
Case 52: Increased Susceptibility to Candida Infections
Case 53: LPS-Responsive Beige-Like Anchor (LRBA) Deficiency
Case 54: T Cell Signaling Defects
Case 55: Channelopathies
Answers
Figure Acknowledgments
Index

About the Author

Raif S. Geha, Luigi Notarangelo

Raif S. Geha, MD, is the James L. Gamble Professor of Pediatrics at the Harvard Medical School and chief of the Division of Immunology, Allergy, and Rheumatology at Boston Children’s Hospital. He combines clinical practice with research on immunodeficiency in patient and transgenic mice, and investigation of the pathogenesis of atopic dermatitis.

Luigi D. Notarangelo, MD, is chief of the Laboratory of Clinical Immunology and Microbiology at the National Institute of Allergy and Infectious Diseases, National Institute of Health. He is a leader in the study of the molecular and cellular mechanisms of human primary immune deficiencies and in the treatment of these disorders. He has served as president of the European Society for Immunology and of the Clinical Immunology Society.

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