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Williams Manual of Hematology 10th Edition - 9781264269204
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Williams Manual of Hematology 10th Edition

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Marcel Levi, Linda Burns, David C. Linch, Kenneth Kaushansky, Marshall Lichtman, Josef Prchal

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ISBN: 978-1264269204 SKU: MB1555 Categories: Haematology, Biology Tags: Haematology, Hematology, Williams, Williams Hematology, Williams Manual of Hematology, Williams Manual of Hematology 10th Edition
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Description

Williams Manual of Hematology 10th Edition

Williams Manual of Hematology Tenth Edition:

A full-color clinical reference covering both common and uncommon blood disorders―distilled from the world’s leading hematology text

Williams Manual of Hematology, Tenth Edition provides a concise, easy-to-navigate compilation of the pathogenic, diagnostic, and therapeutic essentials of blood cell and coagulation protein disorders. Referenced to the classic Williams Hematology, this portable guide has been carefully edited to deliver only the most clinical point-of-care facts, making differential diagnosis faster, easier, and more efficient. This updated edition reflects the latest research and includes more than 100 full-color clinical photographs.

Concise but comprehensive, this complete guide includes sections on:

  • Initial Clinical Evaluation
  • Disorders of Red Cells
  • Disorders of Granulocytes
  • Disorders of Monocytes and Macrophages
  • Principles of Therapy for Neoplastic Hematological Disorders
  • The Clonal Myeloid Disorders
  • The Polyclonal Lymphoid Diseases
  • The Clonal Lymphoid and Plasma Cell Diseases
  • Disorders of Platelet and Hemostasis
  • Disorders of Coagulation Proteins
  • Thrombosis and Antithrombotic Therapy
  • Transfusion and Hemapheresis

Additional ISBNs:

∗ eText ISBN: 1264269218, 978-1264269211, 9781264269211

Table of Contents

Contents

Part I: Clinical Evaluation of the Patient
Chapter 1: Initial Approach to the Patient: History and Physical Examination
Chapter 2: Examination of Blood and Marrow Cells
Chapter 3: Consultative Hematology
Part II: The Organization of the Lymphohematopoietic Tissues
Chapter 4: Structure of the Marrow and the Hematopoietic Microenvironment
Chapter 5: The Organization and Structure of Lymphoid Tissues
Part III: Epochal Hematology
Chapter 6: Hematology of the Fetus and Newborn
Chapter 7: Hematology During Pregnancy
Chapter 8: Hematology in Older Persons
Part IV: Molecular and Cellular Hematology
Chapter 9: Genetic Principles and Molecular Biology
Chapter 10: Genomics and Epigenomics
Chapter 11: Cytogenetic and Genetic Abnormalities
Chapter 12: Application of Big Data and Deep Learning in Hematology
Chapter 13: Metabolism of Hematologic Neoplastic Cells
Chapter 14: Cell Death
Chapter 15: Cell-Cycle Regulation and Hematologic Disorders
Chapter 16: Signal Transduction Pathways
Chapter 17: Hematopoietic Stem Cells, Progenitors, and Cytokines
Chapter 18: The Inflammatory Response
Chapter 19: Innate Immunity
Chapter 20: The Biology of Innate Lymphoid Cells and Natural Killer Cells
Chapter 21: Dendritic Cells and Adaptive Immunity
Part V: Therapeutic Principles
Chapter 22: Immune Checkpoint Inhibitors
Chapter 23: Immune Cell Therapy: Chimeric Antigen Receptor T-Cell Therapy
Chapter 24: Immune Cell Therapy: Dendritic Cell and Natural Killer Cell Therapy
Chapter 25: Vaccine Therapy
Chapter 26: Gene Therapy for Hematologic Diseases
Chapter 27: Regenerative Medicine: Induced Pluripotent Stem Cells And Blood Cell Engineering
Chapter 28: Pharmacology and Toxicity of Antineoplastic Drugs
Chapter 29: Hematopoietic Stem Cell Transplantation
Chapter 30: Therapeutic Apheresis: Indications, Efficacy, and Complications
Chapter 31: Treatment of Infections in the Immunocompromised Host
Chapter 32: Antithrombotic Therapy
Part VI: The Erythrocyte
Chapter 33: Structure and Composition of the Erythrocyte
Chapter 34: Erythropoiesis and Red Cell Turnover
Chapter 35: Clinical Manifestations and Classification of Erythrocyte Disorders
Chapter 36: Aplastic Anemia: Acquired and Inherited
Chapter 37: Pure Red Cell Aplasia
Chapter 38: Anemia of Chronic Disease
Chapter 39: Erythropoietic Effects of Endocrine Disorders
Chapter 40: The Hereditary Dyserythropoietic Anemias
Chapter 41: Paroxysmal Nocturnal Hemoglobinuria
Chapter 42: Folate, Cobalamin, and Megaloblastic Anemias
Chapter 43: Iron Metabolism
Chapter 44: Iron Deficiency and Overload
Chapter 45: Anemia Resulting from Other Nutritional Deficiencies
Chapter 46: Anemia Associated with Marrow Infiltration
Chapter 47: Erythrocyte Membrane Disorders
Chapter 48: Erythrocyte Enzyme Disorders
Chapter 49: Thalassemia: A Disorder of Globin Synthesis
Chapter 50: Disorders of Hemoglobin Structure: Sickle Cell Anemia and Related Abnormalities
Chapter 51: Methemoglobinemia and Other Dyshemoglobinemias
Chapter 52: Fragmentation Hemolytic Anemia
Chapter 53: Erythrocyte Disorders as a Result of Toxic Agents
Chapter 54: Hemolytic Anemia Resulting from Infections with Microorganisms
Chapter 55: Hemolytic Anemia Resulting from Immune Injury
Chapter 56: Alloimmune Hemolytic Disease of the Fetus and Newborn
Chapter 57: Hypersplenism and Hyposplenism
Chapter 58: Primary and Secondary Erythrocytoses/Polycythemias
Chapter 59: The Porphyrias
Chapter 60: Polyclonal and Hereditary Sideroblastic Anemias
Part VII: Neutrophils, Eosinophils, Basophils, and Mast Cells
Chapter 61: Structure and Composition of Neutrophils, Eosinophils, and Basophils
Chapter 62: Classification and Clinical Manifestations of Neutrophil Disorders
Chapter 63: Neutropenia and Neutrophilia
Chapter 64: Disorders of Neutrophil Function
Chapter 65: Eosinophils and Their Disorders
Chapter 66: Basophils and Mast Cells and Their Disorders
Part VIII: Monocytes and Macrophages
Chapter 67: Structure, Receptors, and Functions of Monocytes and Macrophages
Chapter 68: Production, Distribution, and Activation of Monocytes and Macrophages
Chapter 69: Classification and Clinical Manifestations of Disorders of Monocytes and Macrophages
Chapter 70: Monocytosis and Monocytopenia
Chapter 71: Inflammatory and Malignant Histiocytosis
Chapter 72: Gaucher Disease and Related Lysosomal Storage Diseases
Part IX: Lymphocytes and Plasma Cells
Chapter 73: The Structure of Lymphocytes and Plasma Cells
Chapter 74: Lymphopoiesis
Chapter 75: Functions of B Lymphocytes and Plasma Cells in Immunoglobulin Production
Chapter 76: Functions of T Lymphocytes: T-Cell Receptors for Antigen
Chapter 77: Classification and Clinical Manifestations of Lymphocyte and Plasma Cell Disorders
Chapter 78: Lymphocytosis and Lymphocytopenia
Chapter 79: Immunodeficiency Diseases
Chapter 80: Hematologic Manifestations of Human Immunodeficiency Virus and the Acquired Immunodeficiency Syndrome
Chapter 81: Mononucleosis Syndromes
Part X: Malignant Myeloid Diseases
Chapter 82: Classification and Clinical Manifestations of the Clonal Myeloid Disorders
Chapter 83: Polycythemia Vera
Chapter 84: Essential Thrombocythemia
Chapter 85: Primary Myelofibrosis
Chapter 86: Myelodysplastic Syndromes
Chapter 87: Acute Myelogenous Leukemia
Chapter 88: Chronic Myelogenous Leukemia and Related Disorders
Part XI: Malignant Lymphoid Diseases
Chapter 89: Classification of Malignant Lymphoid Disorders
Chapter 90: Acute Lymphoblastic Leukemia
Chapter 91: Chronic Lymphocytic Leukemia
Chapter 92: Hairy Cell Leukemia
Chapter 93: Large Granular Lymphocytic Leukemia
Chapter 94: General Considerations of Lymphomas: Incidence Rates, Etiology, Diagnosis, Staging, and Primary Extranodal Disease
Chapter 95: Pathology of Lymphomas
Chapter 96: Hodgkin Lymphoma
Chapter 97: Diffuse Large B-Cell Lymphoma and Related Diseases
Chapter 98: Follicular Lymphoma
Chapter 99: Mantle Cell Lymphoma
Chapter 100: Marginal Zone B-Cell Lymphomas
Chapter 101: Burkitt Lymphoma
Chapter 102: Cutaneous T-Cell Lymphoma (Mycosis Fungoides and Sézary Syndrome)
Chapter 103: Mature T-Cell and Natural Killer Cell Lymphomas
Chapter 104: Plasma Cell Neoplasms: General Considerations
Chapter 105: Essential Monoclonal Gammopathy
Chapter 106: Myeloma
Chapter 107: Immunoglobulin Light Chain Amyloidosis
Chapter 108: Macroglobulinemia
Chapter 109: Heavy-Chain Disease
Part XII: Hemostasis and Thrombosis
Chapter 110: Megakaryopoiesis and Thrombopoiesis
Chapter 111: Platelet Morphology, Biochemistry, and Function
Chapter 112: Molecular Biology and Biochemistry of the Coagulation Factors and Pathways of Hemostasis
Chapter 113: Control of Coagulation Reactions
Chapter 114: Vascular Function in Hemostasis
Chapter 115: Classification, Clinical Manifestations, and Evaluation of Disorders of Hemostasis
Chapter 116: Thrombocytopenia
Chapter 117: Heparin-Induced Thrombocytopenia
Chapter 118: Hereditary and Reactive Thrombocytosis
Chapter 119: Inherited Platelet Disorders
Chapter 120: Acquired Qualitative Platelet Disorders
Chapter 121: The Vascular Purpuras
Chapter 122: Hemophilia A and Hemophilia B
Chapter 123: Inherited Deficiencies of Coagulation Factors II, V, V+VIII, VII, X, XI, and XIII
Chapter 124: Hereditary Fibrinogen Abnormalities
Chapter 125: VON Willebrand Disease
Chapter 126: Antibody-Mediated Coagulation Factor Deficiencies
Chapter 127: Disseminated Intravascular Coagulation
Chapter 128: Thrombotic Microangiopathies
Chapter 129: Hemolytic Uremic Syndrome
Chapter 130: Hemostatic Alterations in Liver Diseases and Liver Transplantation
Chapter 131: Hereditary Thrombophilia
Chapter 132: The Antiphospholipid Syndrome
Chapter 133: Venous Thrombosis
Chapter 134: Atherothrombosis: Disease Initiation, Progression, and Treatment
Chapter 135: Fibrinolysis and Thrombolysis
Part XIII: Transfusion Medicine
Chapter 136: Erythrocyte Antigens and Antibodies
Chapter 137: Human Leukocyte and Platelet Antigens
Chapter 138: Blood Procurement and Red Cell Transfusion
Chapter 139: Preservation and Clinical use of Platelets
Chapter 140: Using Plasma and Plasma Component Therapy

About the Author

Marshall Lichtman, Kenneth Kaushansky, Josef Prchal, Marcel Levi, Linda Burns, David C. Linch

Senior Vice President, Health Sciences Dean, School of Medicine Stony Brook University Stony Brook, NY

Chairman, Department of MedicineAcademic Medical CenterUniversity of AmsterdamAmsterdam, The Netherlands

Marshall A. Lichtman, MD, is past president of the American Society of Hematology, and Emeritus Dean of the University of Rochester School of Medicine in Rochester, NY.

Kenneth Kaushansky,MD,is past president of the American Society of Hematology, dean of the School of Medicine and senior vice president of Health Sciences at State University of New York at Stony Brook.

Josef T. Prchal, MD,is a professor in the Division of Hematology and Hematologic Malignancies, Department of Internal Medicine at the University of Utah, and a Huntsman Cancer Institute Investigator.

Marcel M. Levi MD, PhD,is CEO and professor of medicine at University College of London Hospitals, London, UK; and professor of medicine at the Academic Medical Center of the University of Amsterdam, The Netherlands.

Linda J. Burns,MD, is vice president and medical director of Health Services Research, National Marrow Donor Program/Be the Match and former President of the American Society of Hematology.

David C. Linch,MD,is professor of hematology and head of the Department of Hematology at University College London Cancer Institute, London, UK.

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