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Casarett & Doull's Toxicology: The Basic Science of Poisons 9th Edition - 9781259863745
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McGraw-Hill Education

Casarett & Doull’s Toxicology: The Basic Science of Poisons 9th Edition

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Author(s)

Curtis Klaassen

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McGraw-Hill Education

ISBN-10

1259863743

ISBN-13

978-1259863745

Pages

1639

Language

English

Edition

9th edition | 2018

File Size

280 MB

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ISBN: 978-1259863745 SKU: MB1575 Category: Pharmacology Tags: Casarett & Doull, Casarett & Doull's Toxicology, Casarett & Doull's Toxicology 9th Edition, Casarett & Doull's Toxicology: The Basic Science of Poisons, Casarett & Doull's Toxicology: The Basic Science of Poisons 9th Edition, Pharmacology, Toxicology
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Description

Casarett & Doull’s Toxicology: The Basic Science of Poisons 9th Edition

Casarett & Doull’s Toxicology: The Basic Science of Poisons Ninth Edition:

Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition equips you with an unsurpassed understanding of modern toxicology, including the key principles, concepts, mechanisms, chemical-specific toxicity, and modes of thought that are the foundation of the discipline. This trusted classic not only delivers a comprehensive review of the essential components of toxicology, it offers the most up-to-date, revealing, and in-depth look at the systemic responses of toxic substance available anywhere.

Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition is logically divided into seven sections:

  • General Principles of Toxicology
  • Disposition of Toxicants
  • Non-Organ Directed Toxicity
  • Target Organ Toxicity
  • Toxic Agents
  • Environmental Toxicology
  • Applications of Toxicology

Many new contributors capture the progress made in toxicology over the past few years:
This edition is markedly updated from the previous edition, with more than one-third of the chapters authored by scientists who have not made previous contributions to the book.

Sharing their expertise, they deliver dynamic new coverage of the importance of apoptosis, autophagy, cytokines, growth factors, oncogenes, cell cycling, receptors, gene regulation, protective mechanisms, repair mechanisms, transcription factors, signaling pathways, transgenic mice, knock-out mice, humanized mice, polymorphisms, microarray technology, second-generation sequencing, genomics, proteomics, epigenetics, exposome, microbiota, read across, adverse outcome pathways, high-content screening, computational toxicology, innovative test methods, and organ-on-a-chip in understanding the mechanisms of toxicity and the regulation of chemicals.
A true “essential”
If you are in need of an up-to-date, all-in-one overview of the biomedical and environmental aspects of toxicology – written by experts, and presented in full color, your search ends here.


Additional ISBNs:

∗ eText ISBN: 1259863751, 978-1259863752, 9781259863752

Table of Contents

Contents

Cover
Title Page
Copyright Page
History and Dedication
Contents
Contributors
Preface
Preface to the First Edition
Unit I General Principles of Toxicology
1. The Evolving Journey of Toxicology: A Historical Glimpse
2. Principles of Toxicology
3. Mechanisms of Toxicity
4. Risk Assessment
Unit II Disposition of Toxicants
5 Absorption, Distribution, and Excretion of Toxicants
6 Biotransformation of Xenobiotics
7 Toxicokinetics
Unit III Non-Organ-Directed Toxicity
8 Chemical Carcinogenesis
9 Genetic Toxicology
10 Developmental Toxicology
Unit IV Target Organ Toxicity
11 Toxic Responses of the Blood
12 Toxic Responses of the Immune System
13 Toxic Responses of the Liver
14 Toxic Responses of the Kidney
15 Toxic Responses of the Respiratory System
16 Toxic Responses of the Nervous System
17 Toxic Responses of the Cornea, Retina, and Central Visual System
18 Toxic Responses of the Heart and Vascular System
19 Toxic Responses of the Skin
20 Toxic Responses of the Endocrine System
21 Toxic Responses of the Reproductive System
Unit V Toxic Agents
22 Toxic Effects of Pesticides
23 Toxic Effects of Metals
24 Toxic Effects of Solvents and Vapors
25 Toxic Effects of Radiation and Radioactive Materials
26 Toxic Effects of Plants and Animals
27 Food Toxicology: Fundamental and Regulatory Aspects
28 Toxic Effects of Calories
29 Nanoparticle Toxicology
Unit VI Environmental Toxicology
30 Ecotoxicology
31 Air Pollution
Unit VII Applications of Toxicology
32 Analytical and Forensic Toxicology
33 Clinical Toxicology
34 Occupational Toxicology
35 Regulatory Toxicology
Index

About the Author

Curtis Klaassen

Curtis Klaassen, PhD, University Distinguished Professor and Chair; Department of Pharmacology, Toxicology, and Therapeutics; Kansas University School of Medicine.

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